目标为可以处理多答题问题的临床问答（QA）系统的开发和评估创建数据集。我们利用2018年国家NLP临床挑战（N2C2）语料库的注释关系来产生QA数据集。 1-0和1-o-n药物 - 理性关系形成了不可批售和多答案的条目，它代表了现有临床QA数据集缺乏的具有挑战性的情景。结果结果rxwhyqa dataSet包含91,440个QA条目，其中一半是未签发的，并且应答的21％（n = 19,269）需要多个答案。数据集符合社区审查的斯坦福问题应答DataSet（Squad）格式。讨论RXWhyQA对于比较需要处理零和多答案挑战的不同系统非常有用，要求对误报和假阴性答案的双重缓解。结论我们创建并共用了一个临床QA数据集，重点是多答题问题，以代表真实世界的情景。

ICECUBE是一种用于检测1 GEV和1 PEV之间大气和天体中微子的光学传感器的立方公斤阵列，该阵列已部署1.45 km至2.45 km的南极的冰盖表面以下1.45 km至2.45 km。来自ICE探测器的事件的分类和重建在ICeCube数据分析中起着核心作用。重建和分类事件是一个挑战，这是由于探测器的几何形状，不均匀的散射和冰中光的吸收，并且低于100 GEV的光，每个事件产生的信号光子数量相对较少。为了应对这一挑战，可以将ICECUBE事件表示为点云图形，并将图形神经网络（GNN）作为分类和重建方法。 GNN能够将中微子事件与宇宙射线背景区分开，对不同的中微子事件类型进行分类，并重建沉积的能量，方向和相互作用顶点。基于仿真，我们提供了1-100 GEV能量范围的比较与当前ICECUBE分析中使用的当前最新最大似然技术，包括已知系统不确定性的影响。对于中微子事件分类，与当前的IceCube方法相比，GNN以固定的假阳性速率（FPR）提高了信号效率的18％。另外，GNN在固定信号效率下将FPR的降低超过8（低于半百分比）。对于能源，方向和相互作用顶点的重建，与当前最大似然技术相比，分辨率平均提高了13％-20％。当在GPU上运行时，GNN能够以几乎是2.7 kHz的中位数ICECUBE触发速率的速率处理ICECUBE事件，这打开了在在线搜索瞬态事件中使用低能量中微子的可能性。

关于强盗算法最佳设计的许多文献都是基于最小化预期遗憾的基础。众所周知，在某些指数家庭中最佳的设计可以实现预期的遗憾，即以LAI-ROBBINS下降的速度在ARM游戏数量上进行对数增长。在本文中，我们表明，当人们使用这种优化的设计时，相关算法的遗憾分布必然具有非常沉重的尾巴，特别是cauchy分布的尾巴。此外，对于$ p> 1 $，遗憾分布的$ p $'瞬间增长速度要比多层型的速度快得多，尤其是作为ARM播放总数的力量。我们表明，优化的UCB强盗设计在另一种意义上也是脆弱的，即，当问题甚至略有指定时，遗憾的增长可能比传统理论所建议的要快得多。我们的论点是基于标准的量化想法，并表明最有可能的遗憾变得比预期的要大的方法是最佳手臂在前几只手臂比赛中返回低于平均水平的奖励，从而导致算法相信这一点手臂是最佳的。为了减轻暴露的脆弱性问题，我们表明可以修改UCB算法，以确保对错误指定的理想程度。在此过程中，我们还提供了UCB勘探数量与产生后悔分布的尾声之间的巨大权衡。

深度强化学习（RL）导致了许多最近和开创性的进步。但是，这些进步通常以培训的基础体系结构的规模增加以及用于训练它们的RL算法的复杂性提高，而均以增加规模的成本。这些增长反过来又使研究人员更难迅速原型新想法或复制已发表的RL算法。为了解决这些问题，这项工作描述了ACME，这是一个用于构建新型RL算法的框架，这些框架是专门设计的，用于启用使用简单的模块化组件构建的代理，这些组件可以在各种执行范围内使用。尽管ACME的主要目标是为算法开发提供一个框架，但第二个目标是提供重要或最先进算法的简单参考实现。这些实现既是对我们的设计决策的验证，也是对RL研究中可重复性的重要贡献。在这项工作中，我们描述了ACME内部做出的主要设计决策，并提供了有关如何使用其组件来实施各种算法的进一步详细信息。我们的实验为许多常见和最先进的算法提供了基准，并显示了如何为更大且更复杂的环境扩展这些算法。这突出了ACME的主要优点之一，即它可用于实现大型，分布式的RL算法，这些算法可以以较大的尺度运行，同时仍保持该实现的固有可读性。这项工作提出了第二篇文章的版本，恰好与模块化的增加相吻合，对离线，模仿和从演示算法学习以及作为ACME的一部分实现的各种新代理。

Making histopathology image classifiers robust to a wide range of real-world variability is a challenging task. Here, we describe a candidate deep learning solution for the Mitosis Domain Generalization Challenge 2022 (MIDOG) to address the problem of generalization for mitosis detection in images of hematoxylin-eosin-stained histology slides under high variability (scanner, tissue type and species variability). Our approach consists in training a rotation-invariant deep learning model using aggressive data augmentation with a training set enriched with hard negative examples and automatically selected negative examples from the unlabeled part of the challenge dataset. To optimize the performance of our models, we investigated a hard negative mining regime search procedure that lead us to train our best model using a subset of image patches representing 19.6% of our training partition of the challenge dataset. Our candidate model ensemble achieved a F1-score of .697 on the final test set after automated evaluation on the challenge platform, achieving the third best overall score in the MIDOG 2022 Challenge.

Supervised Question Answering systems (QA systems) rely on domain-specific human-labeled data for training. Unsupervised QA systems generate their own question-answer training pairs, typically using secondary knowledge sources to achieve this outcome. Our approach (called PIE-QG) uses Open Information Extraction (OpenIE) to generate synthetic training questions from paraphrased passages and uses the question-answer pairs as training data for a language model for a state-of-the-art QA system based on BERT. Triples in the form of <subject, predicate, object> are extracted from each passage, and questions are formed with subjects (or objects) and predicates while objects (or subjects) are considered as answers. Experimenting on five extractive QA datasets demonstrates that our technique achieves on-par performance with existing state-of-the-art QA systems with the benefit of being trained on an order of magnitude fewer documents and without any recourse to external reference data sources.

While the capabilities of autonomous systems have been steadily improving in recent years, these systems still struggle to rapidly explore previously unknown environments without the aid of GPS-assisted navigation. The DARPA Subterranean (SubT) Challenge aimed to fast track the development of autonomous exploration systems by evaluating their performance in real-world underground search-and-rescue scenarios. Subterranean environments present a plethora of challenges for robotic systems, such as limited communications, complex topology, visually-degraded sensing, and harsh terrain. The presented solution enables long-term autonomy with minimal human supervision by combining a powerful and independent single-agent autonomy stack, with higher level mission management operating over a flexible mesh network. The autonomy suite deployed on quadruped and wheeled robots was fully independent, freeing the human supervision to loosely supervise the mission and make high-impact strategic decisions. We also discuss lessons learned from fielding our system at the SubT Final Event, relating to vehicle versatility, system adaptability, and re-configurable communications.

While the brain connectivity network can inform the understanding and diagnosis of developmental dyslexia, its cause-effect relationships have not yet enough been examined. Employing electroencephalography signals and band-limited white noise stimulus at 4.8 Hz (prosodic-syllabic frequency), we measure the phase Granger causalities among channels to identify differences between dyslexic learners and controls, thereby proposing a method to calculate directional connectivity. As causal relationships run in both directions, we explore three scenarios, namely channels' activity as sources, as sinks, and in total. Our proposed method can be used for both classification and exploratory analysis. In all scenarios, we find confirmation of the established right-lateralized Theta sampling network anomaly, in line with the temporal sampling framework's assumption of oscillatory differences in the Theta and Gamma bands. Further, we show that this anomaly primarily occurs in the causal relationships of channels acting as sinks, where it is significantly more pronounced than when only total activity is observed. In the sink scenario, our classifier obtains 0.84 and 0.88 accuracy and 0.87 and 0.93 AUC for the Theta and Gamma bands, respectively.

Vocal Bursts -- short, non-speech vocalizations that convey emotions, such as laughter, cries, sighs, moans, and groans -- are an often-overlooked aspect of speech emotion recognition, but an important aspect of human vocal communication. One barrier to study of these interesting vocalizations is a lack of large datasets. I am pleased to introduce the EmoGator dataset, which consists of 32,040 samples from 365 speakers, 16.91 hours of audio; each sample classified into one of 30 distinct emotion categories by the speaker. Several different approaches to construct classifiers to identify emotion categories will be discussed, and directions for future research will be suggested. Data set is available for download from https://github.com/fredbuhl/EmoGator.

Charisma is considered as one's ability to attract and potentially also influence others. Clearly, there can be considerable interest from an artificial intelligence's (AI) perspective to provide it with such skill. Beyond, a plethora of use cases opens up for computational measurement of human charisma, such as for tutoring humans in the acquisition of charisma, mediating human-to-human conversation, or identifying charismatic individuals in big social data. A number of models exist that base charisma on various dimensions, often following the idea that charisma is given if someone could and would help others. Examples include influence (could help) and affability (would help) in scientific studies or power (could help), presence, and warmth (both would help) as a popular concept. Modelling high levels in these dimensions for humanoid robots or virtual agents, seems accomplishable. Beyond, also automatic measurement appears quite feasible with the recent advances in the related fields of Affective Computing and Social Signal Processing. Here, we, thereforem present a blueprint for building machines that can appear charismatic, but also analyse the charisma of others. To this end, we first provide the psychological perspective including different models of charisma and behavioural cues of it. We then switch to conversational charisma in spoken language as an exemplary modality that is essential for human-human and human-computer conversations. The computational perspective then deals with the recognition and generation of charismatic behaviour by AI. This includes an overview of the state of play in the field and the aforementioned blueprint. We then name exemplary use cases of computational charismatic skills before switching to ethical aspects and concluding this overview and perspective on building charisma-enabled AI.